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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3775370
Molecular formula	C21H15FN2O5S
IUPAC name	6-[(3-fluoro-6H-benzo[c][1,5]benzoxazepin-11-yl)sulfonyl]-4H-1,4-benzoxazin-3-one
Molecular weight	426.418
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	2.8
Synonyms	BDBM50154369
Inchi Key	BKJYVCPUKCJUBJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H15FN2O5S/c22-14-5-7-18-20(9-14)28-11-13-3-1-2-4-17(13)24(18)30(26,27)15-6-8-19-16(10-15)23-21(25)12-29-19/h1-10H,11-12H2,(H,23,25)
PubChem CID	127030225
ChEMBL	CHEMBL3775370
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
522345	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
522344	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
522343	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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