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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL179648
Molecular formula	C21H26N2O
IUPAC name	1-benzyl-4-(3,4-dihydro-2H-chromen-2-ylmethyl)piperazine
Molecular weight	322.452
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.7
Synonyms	AJZBPCAHQHCXMX-UHFFFAOYSA-N 1-[(chroman-2-yl)methyl]-4-benzylpiperazine BDBM50159018 1-benzyl-4-((3,4-dihydro-2H-chromen-2-yl)methyl)piperazine D03LDH 1-Benzyl-4-chroman-2-ylmethyl-piperazine SCHEMBL8031431 [ Show all ]
Inchi Key	AJZBPCAHQHCXMX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H26N2O/c1-2-6-18(7-3-1)16-22-12-14-23(15-13-22)17-20-11-10-19-8-4-5-9-21(19)24-20/h1-9,20H,10-17H2
PubChem CID	10758200
ChEMBL	CHEMBL179648
IUPHAR	N/A
BindingDB	50159018
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7345	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
7346	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
7348	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
7347	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
7349	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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