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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL248272
Molecular formula	C26H33N3O5
IUPAC name	6-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]-N-[2-(dimethylamino)ethyl]-7-methoxy-1-benzofuran-2-carboxamide
Molecular weight	467.566
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.3
Synonyms	N/A
Inchi Key	AGQQEUUAHFMHGL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H33N3O5/c1-28(2)11-9-27-26(30)23-13-18-6-7-19(24(33-5)25(18)34-23)15-29-10-8-17-12-21(31-3)22(32-4)14-20(17)16-29/h6-7,12-14H,8-11,15-16H2,1-5H3,(H,27,30)
PubChem CID	44438176
ChEMBL	CHEMBL248272
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5126	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
5125	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
5124	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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