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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL425069
Molecular formula	C27H28ClN5O3
IUPAC name	N-[3-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzodiazepin-11-yl]-2,6-dimethoxybenzamide
Molecular weight	506.003
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.3
Synonyms	BDBM50190059 N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-2,6-dimethoxy-benzamide
Inchi Key	ADLYXAHODXNVQT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H28ClN5O3/c1-31-13-15-32(16-14-31)26-19-7-4-5-8-21(19)33(22-12-11-18(28)17-20(22)29-26)30-27(34)25-23(35-2)9-6-10-24(25)36-3/h4-12,17H,13-16H2,1-3H3,(H,30,34)
PubChem CID	44415569
ChEMBL	CHEMBL425069
IUPHAR	N/A
BindingDB	50190059
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2407	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
2406	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
2405	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
2409	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
2404	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
2408	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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