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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL214996
Molecular formula	C23H28N4O
IUPAC name	[4-[4-(3,4-dimethylpiperazin-1-yl)anilino]-2-methylquinolin-3-yl]methanol
Molecular weight	376.504
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.2
Synonyms	{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-2-methylquinolin-3-yl}methanol BDBM50196129 SCHEMBL6822398
Inchi Key	BSEZBDDBKUJHQP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H28N4O/c1-16-14-27(13-12-26(16)3)19-10-8-18(9-11-19)25-23-20-6-4-5-7-22(20)24-17(2)21(23)15-28/h4-11,16,28H,12-15H2,1-3H3,(H,24,25)
PubChem CID	10045088
ChEMBL	CHEMBL214996
IUPHAR	N/A
BindingDB	50196129
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
31599	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
31597	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
31598	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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