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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	UNII-2L5SGH4CVS
Molecular formula	C22H31N5O2
IUPAC name	2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino]-N,N-dimethylpyridine-3-carboxamide
Molecular weight	397.523
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.1
Synonyms	SCHEMBL9027734 723731-91-7 CHEMBL329160 2-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propylamino)-N,N-dimethylnicotinamide N,N-Dimethyl-2-[3-[4-(2-methoxyphenyl)piperazino]propylamino]nicotinamide 3-Pyridinecarboxamide, 2-((3-(4-(2-methoxyphenyl)-1-piperazinyl)propyl)amino)-N,N-dimethyl- BDBM50408229 L001538 2-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino}-N,N-dimethylnicotinamide RS-97078 free base MNIPVWNHCWNYRB-UHFFFAOYSA-N 2L5SGH4CVS [ Show all ]
Inchi Key	MNIPVWNHCWNYRB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H31N5O2/c1-25(2)22(28)18-8-6-11-23-21(18)24-12-7-13-26-14-16-27(17-15-26)19-9-4-5-10-20(19)29-3/h4-6,8-11H,7,12-17H2,1-3H3,(H,23,24)
PubChem CID	9865577
ChEMBL	CHEMBL329160
IUPHAR	N/A
BindingDB	50408229
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
209725	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
209724	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
209727	Alpha-1A adrenergic receptor	O02824	ADRA1A	Oryctolagus cuniculus (Rabbit)	466
209726	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
209728	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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