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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Ifenprodil
Molecular formula	C21H27NO2
IUPAC name	4-[2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol
Molecular weight	325.452
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.9
Synonyms	Ifenprodil (INN) J-015034 NCGC00024643-05 RC 61-91 1-Methyl-2-hydroxy-2-(4-hydroxyphenyl)ethyl-1-(4-benzylpiperidine) Tox21_110915 23210-58-4 925913-11-7 C-19841 Creocral DSSTox_RID_81034 FT-0601591 ifenprodil tartrate LS-115339 NCGC00024643-10 SCHEMBL34010 1-Piperidineethanol, alpha-(4-hydroxyphenyl)-beta-methyl-4-(phenylmethyl)- (9CI) UYNVMODNBIQBMV-UHFFFAOYSA-N 4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol Alpha 1-PI CCG-204747 D0I0DL I06-0297 Ifenprodilum NCGC00024643-03 PDSP2_000646 (+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol] SR-01000075169-11 210I562 4-[2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol BDBM50083351 CHEMBL305187 DSSTox_CID_25656 IFENPRODIL HEMITARTRATE KB-52538 NCGC00024643-06 RC-61-91 1-Piperidineethanol, 4-benzyl-alpha-(p-hydroxyphenyl)-beta-methyl- Tox21_110915_1 4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phenol AC1L1GHT CAS-23210-56-2 D08064 DTXSID2045656 GTPL5472 Ifenprodil tartrate salt MRF-0000097 NCGC00024643-12 SR-01000075169 2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-2-methyl-1-ethanol Vadilex 4-[2-(4-Benzyl-1-piperidyl)-1-hydroxy-propyl]phenol; (2R,3R)-2,3-dihydroxybutanedioic acid alpha-(4-Hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidine ethanol CHEBI:93829 DB08954 Ifenprodilum [INN-Latin] NCGC00024643-04 R8OE3P6O5S (plusmn)-ifenprodil SR-01000075169-3 23210-56-2 61 91 RC BRD-A24191444-045-03-1 ChEMBL_104385 DSSTox_GSID_45656 EINECS 245-491-4 Ifenprodil L-(+)-tartrate L005364 NCGC00024643-07 SBI-0050640.P002 1-Piperidineethanol, alpha-(4-hydroxyphenyl)-beta-methyl-4-(phenylmethyl)- UNII-R8OE3P6O5S 4-Benzyl-alpha-(p-hydroxyphenyl)-beta-methyl-1-piperidineethanol AKOS015895174 CC-29467 D08VCI HMS2089G05 Ifenprodil [INN:DCF] NCGC00024643-02 PDSP1_000654 SR-01000075169-1 2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)propanol 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-phenol AX8042605 Dilvax [ Show all ]
Inchi Key	UYNVMODNBIQBMV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3
PubChem CID	3689
ChEMBL	CHEMBL305187
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
348840	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
348837	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
348832	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
348839	D(1A) dopamine receptor	Q61616	Drd1	Mus musculus (Mouse)	446
348834	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
348833	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
348838	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
348835	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589

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