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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL63449
Molecular formula	C20H28N2O
IUPAC name	1-[(8S)-8-(dipropylamino)-6,7,8,9-tetrahydro-3H-benzo[e]indol-1-yl]ethanone
Molecular weight	312.457
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	4.3
Synonyms	BDBM50044238 S-(-)-1-(8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indol-1-yl)-ethanone
Inchi Key	VMXHWDJFMZJHSQ-INIZCTEOSA-N
Inchi ID	InChI=1S/C20H28N2O/c1-4-10-22(11-5-2)16-8-6-15-7-9-19-20(17(15)12-16)18(13-21-19)14(3)23/h7,9,13,16,21H,4-6,8,10-12H2,1-3H3/t16-/m0/s1
PubChem CID	44305180
ChEMBL	CHEMBL63449
IUPHAR	N/A
BindingDB	50044238
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
359072	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
359074	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
359071	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
359073	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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