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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL14060296
Molecular formula	C21H25ClN2O2
IUPAC name	(2R)-2-[(3-chlorophenoxy)methyl]-4-[2-(2,3-dihydroindol-1-yl)ethyl]morpholine
Molecular weight	372.893
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.1
Synonyms	US9079895, 23r BDBM186933
Inchi Key	QAJBOIGVHPCSNX-HXUWFJFHSA-N
Inchi ID	InChI=1S/C21H25ClN2O2/c22-18-5-3-6-19(14-18)26-16-20-15-23(12-13-25-20)10-11-24-9-8-17-4-1-2-7-21(17)24/h1-7,14,20H,8-13,15-16H2/t20-/m1/s1
PubChem CID	71061729
ChEMBL	N/A
IUPHAR	N/A
BindingDB	186933
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
565790	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
565787	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
565789	5-hydroxytryptamine receptor 2B	Q02152	Htr2b	Mus musculus (Mouse)	479
565788	D(2) dopamine receptor	P61168	Drd2	Mus musculus (Mouse)	444
565786	D(4) dopamine receptor	P51436	Drd4	Mus musculus (Mouse)	387

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