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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CP-293019
Molecular formula	C19H22F2N4O
IUPAC name	(7R,9aS)-7-[(4-fluorophenoxy)methyl]-2-(5-fluoropyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine
Molecular weight	360.409
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.1
Synonyms	GTPL977 CHEMBL66227 (7R,9aalpha)-2-(5-Fluoro-2-pyrimidinyl)-7alpha-(4-fluorophenoxymethyl)octahydro-6H-pyrido[1,2-a]pyrazine CP293019 BDBM50069041 SCHEMBL6844226 CP 293019 (7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-pyrimidin-2-yl)-octahydro-pyrido[1,2-a]pyrazine D0Z7AW 7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-pyrimidin-2-yl)-octahydro-pyrido[1,2-a]pyrazine (CP-293019) (7R,9aS)-7-[(4-fluorophenoxy)methyl]-2-(5-fluoropyrimidin-2-yl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine [ Show all ]
Inchi Key	QXWNESOGWFJDFR-PBHICJAKSA-N
Inchi ID	InChI=1S/C19H22F2N4O/c20-15-2-5-18(6-3-15)26-13-14-1-4-17-12-25(8-7-24(17)11-14)19-22-9-16(21)10-23-19/h2-3,5-6,9-10,14,17H,1,4,7-8,11-13H2/t14-,17+/m1/s1
PubChem CID	9820261
ChEMBL	CHEMBL66227
IUPHAR	977
BindingDB	50069041
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
289542	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
289538	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
289539	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
289541	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
289540	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
554711	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387

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