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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL142277
Molecular formula	C24H29N5OS
IUPAC name	N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-2,3-dihydro-1H-indole-7-carboxamide
Molecular weight	435.59
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.3
Synonyms	N-[4-[4-(1,2-Benzisothiazol-3-yl)piperazino]butyl]-2,3-dihydro-1H-indole-7-carboxamide 161940-18-7 SCHEMBL9209784 1h-indole-7-carboxamide,n-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]-2,3-dihydro- BDBM50054704 KB-265175 ZINC12356413 2,3-Dihydro-1H-indole-7-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide [ Show all ]
Inchi Key	VIHHTBYBRANJQC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29N5OS/c30-24(20-8-5-6-18-10-12-25-22(18)20)26-11-3-4-13-28-14-16-29(17-15-28)23-19-7-1-2-9-21(19)31-27-23/h1-2,5-9,25H,3-4,10-17H2,(H,26,30)
PubChem CID	11797166
ChEMBL	CHEMBL142277
IUPHAR	N/A
BindingDB	50054704
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
355884	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
355885	D(2) dopamine receptor	P61168	Drd2	Mus musculus (Mouse)	444

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