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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	EF-7412
Molecular formula	C22H33N5O4S
IUPAC name	N-[3-[4-[4-(1,3-dioxo-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazol-2-yl)butyl]piperazin-1-yl]phenyl]ethanesulfonamide
Molecular weight	463.597
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	1.5
Synonyms	EF 7412 L018229 221452-76-2 SCHEMBL1043154 Ethanesulfonamide, N-(3-(4-(4-(tetrahydro-1,3-dioxo-1H-pyrrolo(1,2-C)imidazol-2(3H)-yl)butyl)-1-piperazinyl)phenyl)-
Inchi Key	APHPLOYRLDEZMD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H33N5O4S/c1-2-32(30,31)23-18-7-5-8-19(17-18)25-15-13-24(14-16-25)10-3-4-11-27-21(28)20-9-6-12-26(20)22(27)29/h5,7-8,17,20,23H,2-4,6,9-16H2,1H3
PubChem CID	9934117
ChEMBL	CHEMBL416266
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10977	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
10979	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
10978	D(2) dopamine receptor	P61168	Drd2	Mus musculus (Mouse)	444

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