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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL91605
Molecular formula	C25H34FN7O2
IUPAC name	4-[3-[4-(4-fluoro-2-methoxyphenyl)piperazin-1-yl]propylamino]-N,N,1,3-tetramethylpyrazolo[3,4-b]pyridine-5-carboxamide
Molecular weight	483.592
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	3.3
Synonyms	BDBM50408197
Inchi Key	JEHYIUUKVDHKND-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H34FN7O2/c1-17-22-23(19(25(34)30(2)3)16-28-24(22)31(4)29-17)27-9-6-10-32-11-13-33(14-12-32)20-8-7-18(26)15-21(20)35-5/h7-8,15-16H,6,9-14H2,1-5H3,(H,27,28)
PubChem CID	10624682
ChEMBL	CHEMBL91605
IUPHAR	N/A
BindingDB	50408197
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
148852	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
148855	Alpha-1A adrenergic receptor	O02824	ADRA1A	Oryctolagus cuniculus (Rabbit)	466
148853	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
148854	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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