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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL356743
Molecular formula	C25H31N5OS
IUPAC name	N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-1,2,3,4-tetrahydroquinoline-8-carboxamide
Molecular weight	449.617
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.7
Synonyms	N-[4-[4-(1,2-Benzisothiazol-3-yl)piperazino]butyl]-1,2,3,4-tetrahydroquinoline-8-carboxamide 1,2,3,4-Tetrahydro-quinoline-8-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide SCHEMBL9213593 BDBM50054710
Inchi Key	RPBVWEILTAVEHF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H31N5OS/c31-25(21-10-5-7-19-8-6-13-26-23(19)21)27-12-3-4-14-29-15-17-30(18-16-29)24-20-9-1-2-11-22(20)32-28-24/h1-2,5,7,9-11,26H,3-4,6,8,12-18H2,(H,27,31)
PubChem CID	10694821
ChEMBL	CHEMBL356743
IUPHAR	N/A
BindingDB	50054710
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
301737	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
301738	D(2) dopamine receptor	P61168	Drd2	Mus musculus (Mouse)	444

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