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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL143075
Molecular formula	C20H25N5OS2
IUPAC name	4-amino-N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]thiophene-3-carboxamide
Molecular weight	415.574
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	3.8
Synonyms	N-[4-[4-(1,2-Benzisothiazol-3-yl)piperazino]butyl]-4-aminothiophene-3-carboxamide 4-Amino-thiophene-3-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide SCHEMBL9210256 BDBM50054715
Inchi Key	ANZGKDRXGOPIJA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H25N5OS2/c21-17-14-27-13-16(17)20(26)22-7-3-4-8-24-9-11-25(12-10-24)19-15-5-1-2-6-18(15)28-23-19/h1-2,5-6,13-14H,3-4,7-12,21H2,(H,22,26)
PubChem CID	10669552
ChEMBL	CHEMBL143075
IUPHAR	N/A
BindingDB	50054715
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10041	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
10042	D(2) dopamine receptor	P61168	Drd2	Mus musculus (Mouse)	444

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