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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL294705
Molecular formula	C23H32N4O4
IUPAC name	8-[2-[2,6-dimethyl-4-(2-nitrophenyl)piperazin-1-yl]ethyl]-8-azaspiro[4.5]decane-7,9-dione
Molecular weight	428.533
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.5
Synonyms	8-{2-[2,6-Dimethyl-4-(2-nitro-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione BDBM50143677
Inchi Key	BFZPCLNPQUOCAP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H32N4O4/c1-17-15-24(19-7-3-4-8-20(19)27(30)31)16-18(2)25(17)11-12-26-21(28)13-23(14-22(26)29)9-5-6-10-23/h3-4,7-8,17-18H,5-6,9-16H2,1-2H3
PubChem CID	11418949
ChEMBL	CHEMBL294705
IUPHAR	N/A
BindingDB	50143677
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
22770	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
22769	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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