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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL220515
Molecular formula	C24H26ClN5O2
IUPAC name	3-[2-[4-(5-chloro-2-methoxyphenyl)piperazin-1-yl]ethyl]-2-methyl-5H-pyrimido[5,4-b]indol-4-one
Molecular weight	451.955
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.6
Synonyms	N/A
Inchi Key	AMDQVJAWEJXJFN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H26ClN5O2/c1-16-26-22-18-5-3-4-6-19(18)27-23(22)24(31)30(16)14-11-28-9-12-29(13-10-28)20-15-17(25)7-8-21(20)32-2/h3-8,15,27H,9-14H2,1-2H3
PubChem CID	16721110
ChEMBL	CHEMBL220515
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8779	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
8780	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
8778	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
8781	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
8782	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
8783	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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