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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1242445
Molecular formula	C26H33N3O4
IUPAC name	1-[[(2R,4R)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]pyrrolidin-2-one
Molecular weight	451.567
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	2.4
Synonyms	BDBM50416778
Inchi Key	AOZOBKDTJZCKJE-GJZUVCINSA-N
Inchi ID	InChI=1S/C26H33N3O4/c1-31-24-11-6-5-10-23(24)28-16-14-27(15-17-28)18-22-19-32-26(33-22,21-8-3-2-4-9-21)20-29-13-7-12-25(29)30/h2-6,8-11,22H,7,12-20H2,1H3/t22-,26+/m1/s1
PubChem CID	52948119
ChEMBL	CHEMBL1242445
IUPHAR	N/A
BindingDB	50416778
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10777	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
10776	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
10781	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
10780	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
10782	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
10778	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
10779	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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