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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL14213
Molecular formula	C26H28N4O3S
IUPAC name	3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-methyl-5-phenylthieno[2,3-d]pyrimidine-2,4-dione
Molecular weight	476.595
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.1
Synonyms	1-Methyl-3-[2-[4-(2-methoxyphenyl)piperazino]ethyl]-5-phenyl-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-2,4-dione BDBM50099324 SCHEMBL8036605 3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-1-methyl-5-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-dione
Inchi Key	BEJGRQHTUSMJBJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H28N4O3S/c1-27-25-23(20(18-34-25)19-8-4-3-5-9-19)24(31)30(26(27)32)17-14-28-12-15-29(16-13-28)21-10-6-7-11-22(21)33-2/h3-11,18H,12-17H2,1-2H3
PubChem CID	9891166
ChEMBL	CHEMBL14213
IUPHAR	N/A
BindingDB	50099324
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21597	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
21598	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
21600	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
21599	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
21596	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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