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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL55629
Molecular formula	C22H27F3N4O3
IUPAC name	5-methyl-3-[[1-[[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]methyl]cyclopropyl]methyl]-1H-pyrimidine-2,4-dione
Molecular weight	452.478
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	2.9
Synonyms	BDBM50220786
Inchi Key	ALXPTLNJYZORDB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H27F3N4O3/c1-16-12-26-20(31)29(19(16)30)14-21(6-7-21)13-27-8-10-28(11-9-27)17-4-2-3-5-18(17)32-15-22(23,24)25/h2-5,12H,6-11,13-15H2,1H3,(H,26,31)
PubChem CID	44298746
ChEMBL	CHEMBL55629
IUPHAR	N/A
BindingDB	50220786
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8643	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
8644	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
8641	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
8642	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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