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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL91989
Molecular formula	C27H32F3N5O2
IUPAC name	N,N-dimethyl-4-[3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propylamino]quinoline-3-carboxamide
Molecular weight	515.581
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	5.3
Synonyms	N/A
Inchi Key	ASVLTVMZMRWUDI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H32F3N5O2/c1-33(2)26(36)21-18-32-22-9-4-3-8-20(22)25(21)31-12-7-13-34-14-16-35(17-15-34)23-10-5-6-11-24(23)37-19-27(28,29)30/h3-6,8-11,18H,7,12-17,19H2,1-2H3,(H,31,32)
PubChem CID	10815708
ChEMBL	CHEMBL91989
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
13575	Alpha-1A adrenergic receptor	O02824	ADRA1A	Oryctolagus cuniculus (Rabbit)	466
13574	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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