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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2153555
Molecular formula	C19H22ClNO5
IUPAC name	N-[[(3S)-5-chloro-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-(2,6-dimethoxyphenoxy)ethanamine
Molecular weight	379.837
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.5
Synonyms	CHEMBL2220895 BDBM50392643
Inchi Key	CQFKZCAKNRCPDY-ZDUSSCGKSA-N
Inchi ID	InChI=1S/C19H22ClNO5/c1-22-15-6-4-7-16(23-2)19(15)24-10-9-21-11-13-12-25-17-8-3-5-14(20)18(17)26-13/h3-8,13,21H,9-12H2,1-2H3/t13-/m0/s1
PubChem CID	71462043
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50392643
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
48028	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
48024	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
48029	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
48025	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
48026	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
48023	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
48027	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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