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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1630940
Molecular formula	C20H25F3N2O5S
IUPAC name	2-methoxy-5-[(2R)-2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethylamino]propyl]benzenesulfonamide
Molecular weight	462.484
Hydrogen bond acceptor	10
Hydrogen bond donor	2
XlogP	3.5
Synonyms	BDBM50417540 SCHEMBL3129427
Inchi Key	CPWQIBJELMVKCH-CQSZACIVSA-N
Inchi ID	InChI=1S/C20H25F3N2O5S/c1-14(11-15-7-8-18(28-2)19(12-15)31(24,26)27)25-9-10-29-16-5-3-4-6-17(16)30-13-20(21,22)23/h3-8,12,14,25H,9-11,13H2,1-2H3,(H2,24,26,27)/t14-/m1/s1
PubChem CID	24897950
ChEMBL	CHEMBL1630940
IUPHAR	N/A
BindingDB	50417540
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
47781	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
47786	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
47784	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
47785	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
47782	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
47783	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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