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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL299454
Molecular formula	C21H30ClN3O
IUPAC name	8-[2-[4-(2-chlorophenyl)piperazin-1-yl]ethyl]-8-azaspiro[4.5]decan-9-one
Molecular weight	375.941
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.1
Synonyms	BDBM50143680 8-{2-[4-(2-Chloro-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decan-7-one
Inchi Key	BYHQOSOPNSLUAD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H30ClN3O/c22-18-5-1-2-6-19(18)24-14-11-23(12-15-24)13-16-25-10-9-21(17-20(25)26)7-3-4-8-21/h1-2,5-6H,3-4,7-17H2
PubChem CID	11234230
ChEMBL	CHEMBL299454
IUPHAR	N/A
BindingDB	50143680
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
35798	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
35797	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
35801	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
35799	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
35800	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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