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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL58384
Molecular formula	C21H27ClIN3O2
IUPAC name	8-[2-[4-(2-chloro-5-iodophenyl)piperazin-1-yl]ethyl]-8-azaspiro[4.5]decane-7,9-dione
Molecular weight	515.82
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.1
Synonyms	8-{2-[4-(2-Chloro-5-iodo-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione BDBM50143726 SCHEMBL6582295
Inchi Key	BVYRODJRYHZDHU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H27ClIN3O2/c22-17-4-3-16(23)13-18(17)25-10-7-24(8-11-25)9-12-26-19(27)14-21(15-20(26)28)5-1-2-6-21/h3-4,13H,1-2,5-12,14-15H2
PubChem CID	9958160
ChEMBL	CHEMBL58384
IUPHAR	N/A
BindingDB	50143726
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
34214	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
34213	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
34212	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
34215	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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