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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Pecazine
Molecular formula	C19H22N2S
IUPAC name	10-[(1-methylpiperidin-3-yl)methyl]phenothiazine
Molecular weight	310.459
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.6
Synonyms	CBHCDHNUZWWAPP-UHFFFAOYSA-N DSSTox_RID_81408 mepasin MPMP Pacatal Base Pecazinum STK386548 1'-{[2-methyl-3-(morpholin-4-ylcarbonyl)-4H-thieno[3,2-b]pyrrol-5-yl]carbonyl}-1,4'-bipiperidine 10-[(1-methylpiperidin-3-yl)methyl]phenothiazine AI3-50131 BAS 01176610 GTPL9782 Mepazine Base Nothiazine Pecatal Phenothiazine, 10-[(1-methyl-3-piperidyl)methyl]- 10-(1-Methyl-piperidin-3-ylmethyl)-10H-phenothiazine 2975-36-2 (mono-hydrochloride) CAS-60-89-9 DSSTox_CID_26177 LS-105610 MLS006011657 P 391 SCHEMBL149976 10-[(1-Methyl-3-piperidyl)-methyl]-phenothiazin AC1L1LQX CCG-108581 DTXSID2046177 Mepazin NCGC00160480-01 Pacatol Pecazinum [INN-Latin] Tox21_111842 10-((1-Methyl-3-piperidyl)methyl)phenothiazine 10H-Phenothiazine, 10-((1-methyl-3-piperidinyl)methyl)- AKOS000280691 BDBM50177661 CHEMBL395110 III-2318 Meprazine Oprea1_067080 Pecazina Probes1_000237 10-(1-Methylpiperidyl-3-methyl)phenothiazine 60-89-9 CBDivE_007551 DSSTox_GSID_46177 MCULE-4399173403 MolPort-001-727-944 Pacatal Pecazine [INN:BAN] SMR004703409 (N-Methyl-3-piperidyl)methylphenothiazine 10-[(1-Methyl-3-piperidyl)methyl]phenothiazine AC1Q7G4S CHEBI:135324 EINECS 200-490-8 MEPAZINE NCIOpen2_008134 Pakatal Phenothiazine, 10-((1-methyl-3-piperidyl)methyl)- US9504692, Mepezine 10-(1-Methyl-3-piperidyl)methyl phenothiazine 10H-Phenothiazine, 10-[(1-methyl-3-piperidinyl)methyl]- AKOS021820849 BRD-A82772293-001-01-6 CTK1A4018 Lacumin Mesapin Oprea1_208564 Pecazina [INN-Spanish] Probes2_000278 10-[(1-Methyl-3-piperidinyl)methyl]-10H-phenothiazine # AB00275848-07 [ Show all ]
Inchi Key	CBHCDHNUZWWAPP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H22N2S/c1-20-12-6-7-15(13-20)14-21-16-8-2-4-10-18(16)22-19-11-5-3-9-17(19)21/h2-5,8-11,15H,6-7,12-14H2,1H3
PubChem CID	6075
ChEMBL	CHEMBL395110
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
443188	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
37872	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
37867	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
37868	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
37875	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
443187	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
37874	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
37879	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
37865	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
37877	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
37869	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
37863	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
37873	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
37866	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
37870	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
37878	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
37864	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
37876	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
37880	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532

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