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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2092927
Molecular formula	C23H27N5OS
IUPAC name	(3R)-3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-5-methylsulfanyl-2,3-dihydroimidazo[1,2-c]quinazoline
Molecular weight	421.563
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.2
Synonyms	BDBM50455096 SCHEMBL6593239 (3R)-3-[[4-(2-Methoxyphenyl)piperazin-1-yl]methyl]-5-(methylthio)-2,3-dihydroimidazo[1,2-c]quinazoline
Inchi Key	DVYBIZHLZSDANU-KRWDZBQOSA-N
Inchi ID	InChI=1S/C23H27N5OS/c1-29-21-10-6-5-9-20(21)27-13-11-26(12-14-27)16-17-15-24-22-18-7-3-4-8-19(18)25-23(30-2)28(17)22/h3-10,17H,11-16H2,1-2H3/t17-/m0/s1
PubChem CID	9953974
ChEMBL	CHEMBL2092927
IUPHAR	N/A
BindingDB	50455096
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
70358	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
70359	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
70360	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450

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