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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL372222
Molecular formula	C25H26ClN5O2
IUPAC name	3-[2-[4-(2-chlorophenyl)piperazin-1-yl]ethyl]-6-(4-methylphenyl)-1,5-dihydropyrrolo[3,2-d]pyrimidine-2,4-dione
Molecular weight	463.966
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.0
Synonyms	3-{2-[4-(2-Chloro-phenyl)-piperazin-1-yl]-ethyl}-6-p-tolyl-1,5-dihydro-pyrrolo[3,2-d]pyrimidine-2,4-dione 3-(2-(4-(2-chlorophenyl)piperazin-1-yl)ethyl)-6-p-tolyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione BDBM50164343
Inchi Key	DSHAQKQNBSNNEJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H26ClN5O2/c1-17-6-8-18(9-7-17)20-16-21-23(27-20)24(32)31(25(33)28-21)15-12-29-10-13-30(14-11-29)22-5-3-2-4-19(22)26/h2-9,16,27H,10-15H2,1H3,(H,28,33)
PubChem CID	11751611
ChEMBL	CHEMBL372222
IUPHAR	N/A
BindingDB	50164343
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
67580	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
67586	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
67587	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
67584	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
67582	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
67579	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
67581	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
67583	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
67585	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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