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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL143026
Molecular formula	C24H24F3N3O3
IUPAC name	N-[(9-amino-6,7-dimethoxy-1,2,3,4-tetrahydroacridin-3-yl)methyl]-4-(trifluoromethyl)benzamide
Molecular weight	459.469
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	4.3
Synonyms	N/A
Inchi Key	FTEVEABUGCVYPW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H24F3N3O3/c1-32-20-10-17-19(11-21(20)33-2)30-18-9-13(3-8-16(18)22(17)28)12-29-23(31)14-4-6-15(7-5-14)24(25,26)27/h4-7,10-11,13H,3,8-9,12H2,1-2H3,(H2,28,30)(H,29,31)
PubChem CID	10479323
ChEMBL	CHEMBL143026
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
86696	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
86701	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
86697	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
86700	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
86698	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
86699	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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