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Name | cinnarizine |
---|---|
Molecular formula | C26H28N2 |
IUPAC name | 1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine |
Molecular weight | 368.524 |
Hydrogen bond acceptor | 2 |
Hydrogen bond donor | 0 |
XlogP | 5.8 |
Synonyms | Mitronal CAS-298-57-7 SR-01000003093-6 NCGC00018187-03 CHEMBL43064 [ Show all ] |
Inchi Key | DERZBLKQOCDDDZ-JLHYYAGUSA-N |
Inchi ID | InChI=1S/C26H28N2/c1-4-11-23(12-5-1)13-10-18-27-19-21-28(22-20-27)26(24-14-6-2-7-15-24)25-16-8-3-9-17-25/h1-17,26H,18-22H2/b13-10+ |
PubChem CID | 1547484 |
ChEMBL | CHEMBL43064 |
IUPHAR | N/A |
BindingDB | 50017657 |
DrugBank | DB00568 |
Structure | |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
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GLASS ID | Name | UniProt | Gene | Species | Length |
---|---|---|---|---|---|
58087 | 5-hydroxytryptamine receptor 1A | P19327 | Htr1a | Rattus norvegicus (Rat) | 422 |
58100 | 5-hydroxytryptamine receptor 2A | P28223 | HTR2A | Homo sapiens (Human) | 471 |
58089 | 5-hydroxytryptamine receptor 2B | P41595 | HTR2B | Homo sapiens (Human) | 481 |
443979 | Alpha-1A adrenergic receptor | P43140 | Adra1a | Rattus norvegicus (Rat) | 466 |
58098 | Alpha-1B adrenergic receptor | P15823 | Adra1b | Rattus norvegicus (Rat) | 515 |
58084 | Alpha-1D adrenergic receptor | P25100 | ADRA1D | Homo sapiens (Human) | 572 |
58086 | Alpha-2A adrenergic receptor | P08913 | ADRA2A | Homo sapiens (Human) | 450 |
58099 | Alpha-2B adrenergic receptor | P18089 | ADRA2B | Homo sapiens (Human) | 450 |
58101 | Alpha-2C adrenergic receptor | P18825 | ADRA2C | Homo sapiens (Human) | 462 |
58104 | D(1B) dopamine receptor | P21918 | DRD5 | Homo sapiens (Human) | 477 |
58095 | D(2) dopamine receptor | P14416 | DRD2 | Homo sapiens (Human) | 443 |
58096 | D(3) dopamine receptor | P35462 | DRD3 | Homo sapiens (Human) | 400 |
58103 | Histamine H1 receptor | P35367 | HRH1 | Homo sapiens (Human) | 487 |
58091 | Histamine H4 receptor | Q9H3N8 | HRH4 | Homo sapiens (Human) | 390 |
58090 | Mu-type opioid receptor | P35372 | OPRM1 | Homo sapiens (Human) | 400 |
58093 | Muscarinic acetylcholine receptor M1 | P11229 | CHRM1 | Homo sapiens (Human) | 460 |
58097 | Muscarinic acetylcholine receptor M1 | P08482 | Chrm1 | Rattus norvegicus (Rat) | 460 |
58092 | Muscarinic acetylcholine receptor M3 | P20309 | CHRM3 | Homo sapiens (Human) | 590 |
58085 | Muscarinic acetylcholine receptor M4 | P08173 | CHRM4 | Homo sapiens (Human) | 479 |
58088 | Muscarinic acetylcholine receptor M5 | P08912 | CHRM5 | Homo sapiens (Human) | 532 |
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