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Ligand

NameCHEMBL125604
Molecular formulaC22H25N5O3
IUPAC name[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(3-methylphenyl)methanone
Molecular weight407.474
Hydrogen bond acceptor7
Hydrogen bond donor1
XlogP3.0
SynonymsN/A
Inchi KeyFCWLZABPRJLQBH-UHFFFAOYSA-N
Inchi IDInChI=1S/C22H25N5O3/c1-14-5-4-6-15(11-14)21(28)26-7-9-27(10-8-26)22-24-17-13-19(30-3)18(29-2)12-16(17)20(23)25-22/h4-6,11-13H,7-10H2,1-3H3,(H2,23,24,25)
PubChem CID10525453
ChEMBLCHEMBL125604
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
75300Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
75301Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
75299Alpha-1D adrenergic receptorP23944Adra1dRattus norvegicus (Rat)561

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