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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL301060
Molecular formula	C28H40N2O8
IUPAC name	8-[4-[(5-methoxy-3,4-dihydro-2H-chromen-3-yl)-propylamino]butyl]-8-azaspiro[4.5]decane-7,9-dione;oxalic acid
Molecular weight	532.634
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	None
Synonyms	LS-22716
Inchi Key	DUEPDEGQJUXNFY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H38N2O4.C2H2O4/c1-3-13-27(20-16-21-22(31-2)9-8-10-23(21)32-19-20)14-6-7-15-28-24(29)17-26(18-25(28)30)11-4-5-12-26;3-1(4)2(5)6/h8-10,20H,3-7,11-19H2,1-2H3;(H,3,4)(H,5,6)
PubChem CID	24833969
ChEMBL	CHEMBL301060
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
68945	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
68943	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
68944	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
68942	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
68947	Alpha-2A adrenergic receptor	Q28838	ADRA2A	Bos taurus (Bovine)	452
68946	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
68948	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444

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