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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL545198
Molecular formula	C23H26N2O4
IUPAC name	2-[2-[(5-methoxy-3,4-dihydro-2H-chromen-3-yl)-propylamino]ethyl]isoindole-1,3-dione
Molecular weight	394.471
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.6
Synonyms	3-[N-PROPYL-N-(2-PHTHALIMIDOETHYL)AMINO]-5-METHOXYCHROMAN SCHEMBL9305322 2-[2-[[(5-Methoxy-3,4-dihydro-2H-1-benzopyran)-3-yl]propylamino]ethyl]-1H-isoindole-1,3(2H)-dione IWAURPBNJCOTMU-UHFFFAOYSA-N CHEMBL264212 2-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl}-isoindole-1,3-dione; hydrochloride LS-84565 BDBM50036845 [ Show all ]
Inchi Key	IWAURPBNJCOTMU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H26N2O4/c1-3-11-24(16-14-19-20(28-2)9-6-10-21(19)29-15-16)12-13-25-22(26)17-7-4-5-8-18(17)23(25)27/h4-10,16H,3,11-15H2,1-2H3
PubChem CID	9977937
ChEMBL	CHEMBL264212
IUPHAR	N/A
BindingDB	50036845
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
143146	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
143152	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
143151	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
143147	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
143148	Alpha-2A adrenergic receptor	Q28838	ADRA2A	Bos taurus (Bovine)	452
143150	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
143149	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444

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