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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL59823
Molecular formula	C24H31N3O3
IUPAC name	7-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-methyl-1,4-benzoxazin-3-one
Molecular weight	409.53
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.6
Synonyms	4-Methyl-7-[4-[4-(2-methoxyphenyl)piperazino]butyl]-2H-1,4-benzoxazine-3(4H)-one BDBM50064577 SCHEMBL9593138 7-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-4-methyl-4H-benzo[1,4]oxazin-3-one
Inchi Key	ILKVBWYXWVXUPJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H31N3O3/c1-25-20-11-10-19(17-23(20)30-18-24(25)28)7-5-6-12-26-13-15-27(16-14-26)21-8-3-4-9-22(21)29-2/h3-4,8-11,17H,5-7,12-16,18H2,1-2H3
PubChem CID	10573576
ChEMBL	CHEMBL59823
IUPHAR	N/A
BindingDB	50064577
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
136068	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
136066	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
136069	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
136067	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444

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