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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL93923
Molecular formula	C28H31FN6O
IUPAC name	1-[2-[4-[1-(4-fluorophenyl)-5-(1-methylpyrazol-3-yl)indol-3-yl]piperidin-1-yl]ethyl]imidazolidin-2-one
Molecular weight	486.595
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.4
Synonyms	BDBM50122799 SCHEMBL6962059 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
Inchi Key	DVICNJMXCZEIQX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H31FN6O/c1-32-12-10-26(31-32)21-2-7-27-24(18-21)25(19-35(27)23-5-3-22(29)4-6-23)20-8-13-33(14-9-20)16-17-34-15-11-30-28(34)36/h2-7,10,12,18-20H,8-9,11,13-17H2,1H3,(H,30,36)
PubChem CID	11049209
ChEMBL	CHEMBL93923
IUPHAR	N/A
BindingDB	50122799
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
69948	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
69954	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
69955	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
69951	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
69950	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
69949	Alpha-1B adrenergic receptor	P18841	ADRA1B	Mesocricetus auratus (Golden hamster)	515
69946	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
69953	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
69947	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
69952	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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