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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL59741
Molecular formula	C20H20F3N3OS
IUPAC name	6-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-3H-1,3-benzothiazol-2-one
Molecular weight	407.455
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.5
Synonyms	SCHEMBL8785701 6-{2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-ethyl}-3H-benzothiazol-2-one BDBM50064573 L006673
Inchi Key	DZKFKYARPPSLED-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H20F3N3OS/c21-20(22,23)15-2-1-3-16(13-15)26-10-8-25(9-11-26)7-6-14-4-5-17-18(12-14)28-19(27)24-17/h1-5,12-13H,6-11H2,(H,24,27)
PubChem CID	10645076
ChEMBL	CHEMBL59741
IUPHAR	N/A
BindingDB	50064573
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
72740	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
72745	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
72742	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
72744	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
72743	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
72741	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444

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