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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL368475
Molecular formula	C20H21F3N2S
IUPAC name	11-(1-methylpiperidin-4-ylidene)-9-(trifluoromethylsulfanyl)-5,6-dihydropyrrolo[2,1-b][3]benzazepine
Molecular weight	378.457
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.2
Synonyms	BDBM50026973 11-(1-Methyl-piperidin-4-ylidene)-9-trifluoromethylsulfanyl-6,11-dihydro-5H-benzo[d]pyrrolo[1,2-a]azepine
Inchi Key	FIYYHZQEJYUHEB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H21F3N2S/c1-24-10-6-15(7-11-24)19-17-13-16(26-20(21,22)23)5-4-14(17)8-12-25-9-2-3-18(19)25/h2-5,9,13H,6-8,10-12H2,1H3
PubChem CID	13141187
ChEMBL	CHEMBL368475
IUPHAR	N/A
BindingDB	50026973
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
79510	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
79511	Alpha-2A adrenergic receptor	Q28838	ADRA2A	Bos taurus (Bovine)	452

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