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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL24619
Molecular formula	C30H34N4O6
IUPAC name	2-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-6,7-dimethoxyquinazolin-4-amine
Molecular weight	546.624
Hydrogen bond acceptor	10
Hydrogen bond donor	1
XlogP	5.0
Synonyms	L013742 2-[1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-6,7-dimethoxy-quinazolin-4-ylamine SCHEMBL7824454 BDBM50057486
Inchi Key	DNJKQYXTRBILHI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H34N4O6/c1-35-23-8-7-17(12-24(23)36-2)11-22-19-14-26(38-4)25(37-3)13-18(19)9-10-34(22)30-32-21-16-28(40-6)27(39-5)15-20(21)29(31)33-30/h7-8,12-16,22H,9-11H2,1-6H3,(H2,31,32,33)
PubChem CID	19063108
ChEMBL	CHEMBL24619
IUPHAR	N/A
BindingDB	50057486
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
64414	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
64412	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
64413	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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