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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	DEXMEDETOMIDINE
Molecular formula	C13H16N2
IUPAC name	5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
Molecular weight	200.285
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	3.1
Synonyms	(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazole 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-3H-imidazole AC1NSJXT Dexdor DexmedetomidineHclC13H16N2.Hcl MPV 1440 SCHEMBL26433 1H-Imidazole, 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]- AKOS026750524 CUHVIMMYOGQXCV-NSHDSACASA-N Dexmedetomidina FT-0666307 Precedex (TN) TPU 006 ZINC4632106 (+)-(S)-4-[1-(2,3-dimethylphenyl) ethyl]-1H -imidazole monohydrochloride 4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazol AB01566872_01 C07450 Dexmedetomidine (USAN/INN) MCULE-5424054659 SB17478 108D583 4-[(s)-1-(2,3-dimethyl-phenyl)-ethyl]-1h-imidazole AK310842 CHEMBL778 Dexdor (TN) Dexmedetomidinum MPV-1440 SW219607-1 1H-Imidazole,5-[(1S)-1-(2,3-dimethylphenyl)ethyl]- API0000529 D00514 Dexmedetomidina [INN-Spanish] GTPL521 RT-012294 UNII-67VB76HONO (+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole AB01566872_02 CHEBI:4466 DB00633 Dexmedetomidine [USAN:INN:BAN] MolPort-035-395-718 SC-78886 113775-47-6 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole AKOS025149503 CTK8E7442 Dexmedetomidin Dexmedetomidinum [INN-Latin] NCGC00025347-01 Tocris-2023 2371AH 67VB76HONO BDBM50085683 D0U3DU KS-00000G0F s3075 UNII-MR15E85MQM component CUHVIMMYOGQXCV-NSHDSACASA-N [ Show all ]
Inchi Key	CUHVIMMYOGQXCV-NSHDSACASA-N
Inchi ID	InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m0/s1
PubChem CID	5311068
ChEMBL	CHEMBL778
IUPHAR	521
BindingDB	50085683
DrugBank	DB00633
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
537249	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
50755	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
50753	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
50754	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
553490	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
50751	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
50756	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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