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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	87394-63-6
Molecular formula	C10H12F3N3
IUPAC name	1-[3-(trifluoromethyl)pyridin-2-yl]piperazine
Molecular weight	231.222
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	1.5
Synonyms	AKOS000142502 KS-00003H37 STL556408 (3-trifluoromethyl-pyridin-2-yl)-piperazine 1-(3-trifluoromethylpyridin-2-yl)piperazine 1-[3-(trifluoromethyl)pyridin-2-yl]piperazine 87394-50-1 A813902 AS-5557 DB-025580 PC9120 TR-038113 1-(3-(trifluoromethyl)pyrid-2-yl)piperazine 1-[3-(trifluoromethyl)-2-pyridyl] piperazine 2-(Piperazin-1-yl)-3-(trifluoromethyl)pyridine AC1Q4JCJ BC4149932 I13-511 SCHEMBL233710 ZX-AP001855 1-(3-trifluoromethyl-2-pyridyl)piperazine 1-[3-(Trifluoromethyl)pyrid-2-yl]piperazine 49N AN-35465 CHEMBL45663 MCULE-4245620170 T67426 1-(3-(trifluoromethyl)-2-pyridyl)piperazine 1-(3trifluoromethylpyridin-2-yl)piperazine 1-[3-(Trifluoromethyl)pyridin-2-yl]piperazine 99% A842124 AX8055489 FRFKCMNQNNNZNO-UHFFFAOYSA-N SBB055620 Z-0023 1-(3-(trifluoromethyl)pyridin-2-yl)piperazine 1-[3-(trifluoromethyl)-2-pyridyl]piperazine 394T636 AJ-74542 BDBM50027018 KB-64766 ST50949999 [3-(trifluoromethyl)-2-pyridyl]piperazine 1-(3-Trifluoromethyl-pyridin-2-yl)-piperazine 1-[3-(trifluoromethyl)pyrid-2-yl]piperazine, AldrichCPR ANW-54905 CTK5F8316 MolPort-000-006-592 TL8005676 1-(3-(trifluoromethyl)-pyridin-2-yl)piperazine 1-[3-(trifluoromethyl)-2-pyridinyl]piperazine 1-[3-(Trifluoromethyl)pyridine-2-yl]piperazine A1-00488 AC1MCRZ8 BBL102605 FT-0607115 SC-82013 ZINC2159227 1-(3-trifluoromethyl-2-pyridinyl)piperazine 1-[3-(trifluoromethyl)pyrid-2-yl]-piperazine 4-(3-trifluoromethyl-pyridin-2-yl)-piperazine [ Show all ]
Inchi Key	FRFKCMNQNNNZNO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C10H12F3N3/c11-10(12,13)8-2-1-3-15-9(8)16-6-4-14-5-7-16/h1-3,14H,4-7H2
PubChem CID	2777786
ChEMBL	CHEMBL45663
IUPHAR	N/A
BindingDB	50027018
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
85376	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
85377	Alpha-2A adrenergic receptor	Q28838	ADRA2A	Bos taurus (Bovine)	452

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