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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL328187
Molecular formula	C27H30FN7O
IUPAC name	1-[2-[4-[1-(4-fluorophenyl)-5-(1-methyltriazol-4-yl)indol-3-yl]piperidin-1-yl]ethyl]imidazolidin-2-one
Molecular weight	487.583
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.9
Synonyms	BDBM50122807 L019142 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,3]triazol-4-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one SCHEMBL6967889
Inchi Key	DUTDDZFCPPOWFH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H30FN7O/c1-32-18-25(30-31-32)20-2-7-26-23(16-20)24(17-35(26)22-5-3-21(28)4-6-22)19-8-11-33(12-9-19)14-15-34-13-10-29-27(34)36/h2-7,16-19H,8-15H2,1H3,(H,29,36)
PubChem CID	9848303
ChEMBL	CHEMBL328187
IUPHAR	N/A
BindingDB	50122807
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
69400	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
69397	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
69396	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
69398	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
69402	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
69395	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
69394	Alpha-1B adrenergic receptor	P18841	ADRA1B	Mesocricetus auratus (Golden hamster)	515
69392	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
69393	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
69399	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
69401	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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