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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1259188
Molecular formula	C27H31FN8O
IUPAC name	1-[2-[4-[1-(4-fluorophenyl)-5-[(2-methyltetrazol-5-yl)methyl]indol-3-yl]piperidin-1-yl]ethyl]imidazolidin-2-one
Molecular weight	502.598
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.6
Synonyms	BDBM50328476 SCHEMBL6954429 1-(2-(4-(1-(4-fluorophenyl)-5-((2-methyl-2H-tetrazol-5-yl)methyl)-1H-indol-3-yl)piperidin-1-yl)ethyl)imidazolidin-2-one
Inchi Key	FGHKCRNDQSRICR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H31FN8O/c1-33-31-26(30-32-33)17-19-2-7-25-23(16-19)24(18-36(25)22-5-3-21(28)4-6-22)20-8-11-34(12-9-20)14-15-35-13-10-29-27(35)37/h2-7,16,18,20H,8-15,17H2,1H3,(H,29,37)
PubChem CID	9913988
ChEMBL	CHEMBL1259188
IUPHAR	N/A
BindingDB	50328476
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
77776	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
77778	Alpha-1B adrenergic receptor	P18841	ADRA1B	Mesocricetus auratus (Golden hamster)	515
77775	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
77777	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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