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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL178376
Molecular formula	C20H19N3
IUPAC name	11-(1-methylpiperidin-4-ylidene)pyrrolo[2,1-b][3]benzazepine-9-carbonitrile
Molecular weight	301.393
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	2.5
Synonyms	HVUHGANPHHJBTO-UHFFFAOYSA-N 11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrrolo[1,2-a]azepine-9-carbonitrile 1-methyl-4-(9-cyano-11H-pyrrolo[2,1-b][3]benzazepin-11-ylidene)piperidine SCHEMBL11208310 1-methyl-4-[9-cyano-11H-pyrrolo[2,1-b] [3]benzazepin-11-ylidene]piperidine BDBM50026971 [ Show all ]
Inchi Key	HVUHGANPHHJBTO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H19N3/c1-22-10-6-17(7-11-22)20-18-13-15(14-21)4-5-16(18)8-12-23-9-2-3-19(20)23/h2-5,8-9,12-13H,6-7,10-11H2,1H3
PubChem CID	12909387
ChEMBL	CHEMBL178376
IUPHAR	N/A
BindingDB	50026971
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
125278	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
125277	Alpha-2A adrenergic receptor	Q28838	ADRA2A	Bos taurus (Bovine)	452

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