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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL13735
Molecular formula	C19H22N4O3S
IUPAC name	3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1H-thieno[2,3-d]pyrimidine-2,4-dione
Molecular weight	386.47
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.2
Synonyms	3-[2-[4-(2-Methoxyphenyl)piperazino]ethyl]-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-2,4-dione BDBM50099320 SCHEMBL10732250 3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-1H-thieno[2,3-d]pyrimidine-2,4-dione
Inchi Key	HESSOZXPIKFUEI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H22N4O3S/c1-26-16-5-3-2-4-15(16)22-10-7-21(8-11-22)9-12-23-18(24)14-6-13-27-17(14)20-19(23)25/h2-6,13H,7-12H2,1H3,(H,20,25)
PubChem CID	13911290
ChEMBL	CHEMBL13735
IUPHAR	N/A
BindingDB	50099320
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
113067	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
113068	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
113069	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
113070	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
113071	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
113072	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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