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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL11592
Molecular formula	C26H38N2O4
IUPAC name	8-[4-[(5-methoxy-3,4-dihydro-2H-chromen-3-yl)-propylamino]butyl]-8-azaspiro[4.5]decane-7,9-dione
Molecular weight	442.6
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.6
Synonyms	ACMC-20mxer PDSP1_000057 8-[4-[(5-methoxy-3,4-dihydro-2H-chromen-3-yl)-propylamino]butyl]-8-azaspiro[4.5]decane-7,9-dione LS-22710 BDBM82368 PDSP2_000057 8-[4-[Propyl(5-methoxychroman-3-yl)amino]butyl]-8-azaspiro[4.5]decane-7,9-dione AC1L3TIS NSC_121851 138277-78-8 CAS_121851 SCHEMBL13532499 8-[4-[[(3S)-5-methoxychroman-3-yl]-propyl-amino]butyl]-8-azaspiro[4.5]decane-7,9-dione L001425 [ Show all ]
Inchi Key	DLLULNTXJPATBC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H38N2O4/c1-3-13-27(20-16-21-22(31-2)9-8-10-23(21)32-19-20)14-6-7-15-28-24(29)17-26(18-25(28)30)11-4-5-12-26/h8-10,20H,3-7,11-19H2,1-2H3
PubChem CID	121852
ChEMBL	CHEMBL11592
IUPHAR	N/A
BindingDB	82368
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
63074	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
63078	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
63077	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
63081	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
63076	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
63079	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
63083	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
63073	Alpha-2A adrenergic receptor	Q28838	ADRA2A	Bos taurus (Bovine)	452
63080	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
63082	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
63075	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444
63084	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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