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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL50456
Molecular formula	C21H19Cl2N5
IUPAC name	7-[4-[(2,4-dichlorophenyl)methyl]piperazin-1-yl]-2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene
Molecular weight	412.318
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.1
Synonyms	BDBM50408158 SCHEMBL8879665
Inchi Key	CKJCINZQXPNLOV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H19Cl2N5/c22-16-6-5-15(17(23)13-16)14-26-9-11-27(12-10-26)21-19-4-2-8-28(19)20-18(25-21)3-1-7-24-20/h1-8,13H,9-12,14H2
PubChem CID	10645335
ChEMBL	CHEMBL50456
IUPHAR	N/A
BindingDB	50408158
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
44086	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
44087	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
44084	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
44085	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
44088	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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