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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL62366
Molecular formula	C20H20N4S
IUPAC name	8-(4-methylpiperazin-1-yl)-4-phenyl-3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene
Molecular weight	348.468
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.8
Synonyms	BDBM50407783 SCHEMBL7296771
Inchi Key	DGWRAIYRSJRMOF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H20N4S/c1-22-10-12-23(13-11-22)19-17-8-5-9-24(17)20-16(21-19)14-18(25-20)15-6-3-2-4-7-15/h2-9,14H,10-13H2,1H3
PubChem CID	11792032
ChEMBL	CHEMBL62366
IUPHAR	N/A
BindingDB	50407783
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
59696	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
59699	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
59697	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
59695	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
59698	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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