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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Binospirone
Molecular formula	C20H26N2O4
IUPAC name	8-[2-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)ethyl]-8-azaspiro[4.5]decane-7,9-dione
Molecular weight	358.438
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.3
Synonyms	AC1L1TVW BRD-A50764878-001-01-4 NCGC00024574-02 CHEBI:91740 Rac-8-[2-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methylamino]ethyl]-8-azaspiro[4.5]decane-7,9-dione methanesulfonate 8-[2-[[(2,3-Dihydro-1,4-benzodioxin)-2-yl]methylamino]ethyl]-8-azaspiro[4.5]decane-7,9-dione Biomol-NT_000113 L002036 SCHEMBL244369 AC1Q6FAE BRD-A50764878-003-01-0 PDSP1_000562 102908-59-8 Binospirone mesylate < Rec INNM CHEMBL1487115 Rac-N-[2-[(1,4-Benzodioxan-2-ylmethyl)amino]ethyl]-1,1-cyclopentanediazetimide methanesulfonate BPBio1_000045 MDL 73005 EF BDBM82518 CAS_124756-23-6 PDSP2_000560 8-[2-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)ethyl]-8-azaspiro[4.5]decane-7,9-dione Binospirone [INN] D05AAM Rac-N-[4-(1,4-Benzodioxan-2-ylmethylamino)ethyl]-3,3-tetramethyleneglutarimide methanesulfonate [ Show all ]
Inchi Key	BVMYCHKQPGEOSI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H26N2O4/c23-18-11-20(7-3-4-8-20)12-19(24)22(18)10-9-21-13-15-14-25-16-5-1-2-6-17(16)26-15/h1-2,5-6,15,21H,3-4,7-14H2
PubChem CID	60769
ChEMBL	N/A
IUPHAR	N/A
BindingDB	82518
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
33884	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
33885	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
33886	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
555610	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471

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