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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL153136
Molecular formula	C26H38N4O2
IUPAC name	1-[[5-[[4-(2-butan-2-yloxyphenyl)piperazin-1-yl]methyl]-1-methylpyrrol-2-yl]methyl]piperidin-2-one
Molecular weight	438.616
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.2
Synonyms	1-[[5-[[4-[2-(1-Methylpropyloxy)phenyl]-1-piperazinyl]methyl]-1-methyl-1H-pyrrol-2-yl]methyl]piperidin-2-one BDBM50001889 SCHEMBL9751028 1-{5-[4-(2-sec-Butoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-piperidin-2-one
Inchi Key	CERMMWURJWEJSR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H38N4O2/c1-4-21(2)32-25-10-6-5-9-24(25)29-17-15-28(16-18-29)19-22-12-13-23(27(22)3)20-30-14-8-7-11-26(30)31/h5-6,9-10,12-13,21H,4,7-8,11,14-20H2,1-3H3
PubChem CID	15124076
ChEMBL	CHEMBL153136
IUPHAR	N/A
BindingDB	50001889
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
40192	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
40193	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
40191	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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