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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 1B
Species	Rattus norvegicus (Rat)
Gene	Htr1b
Synonym	HTR1D2 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 5-HT1Dbeta 5-HT1DB 5-HT1B serotonin receptor 5-HT1B receptor 5-HT1B 5-HT-1B Serotonin receptor 1B [ Show all ]
Disease	N/A for non-human GPCRs
Length	386
Amino acid sequence	MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTG
UniProt	P28564
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3459
IUPHAR	2
DrugBank	N/A

Ligand

Name	CHEMBL62777
Molecular formula	C17H27NO
IUPAC name	7-(dipropylamino)-4-methyl-5,6,7,8-tetrahydronaphthalen-1-ol
Molecular weight	261.409
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	4.5
Synonyms	1,2,3,4-Tetrahydro-2-(dipropylamino)-5-methyl-8-naphthalenol BDBM50280931 7-Dipropylamino-4-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol
Inchi Key	BNMXVEWINKAJLK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H27NO/c1-4-10-18(11-5-2)14-7-8-15-13(3)6-9-17(19)16(15)12-14/h6,9,14,19H,4-5,7-8,10-12H2,1-3H3
PubChem CID	9992840
ChEMBL	CHEMBL62777
IUPHAR	N/A
BindingDB	50280931
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<10000.0 nM	, Bioorg. Med. Chem. Lett., (1993) 3:10:2035	BindingDB,ChEMBL

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